Peptide Active Data Details
Basic Peptide Information
DICL ID
DICL_Pep_04044
Ion Channel
Neuronal acetylcholine receptor subunit alpha-4/beta-2
Peptide Function
Inhibitor
Gene Name
CHRNA4/CHRNB2
Activity Data (nM)
IC50
>10000 nM
Ki
Not available
EC50
Not available
Kd
Not available
Biologically Active
Not specified
Sequence Information
Peptide Sequence
GCCSDPRCAWRC
Peptide UniProt Accession
UniParc
UPI0000035429
Peptide Synonyms/Alias
ImI
Peptide Species
Conus imperialis (Imperial cone)
Peptide Name
Alpha-conotoxin ImI
CAS Number
Not available
Experimental Conditions
pH
pH 7.1 to 7.5
Holding Potential (mV)
–110 mV
Temperature
Room Temperture
Test Method
Patch-clamping
Test Species
Xenopus laevis oocyte
Binding Information
Binding Site
Not specified
Binding Site Residue
Not specified
Ion Channel Information
Gene Abbreviation (ABB)
nAChRs
Ion Channel UniProt Accession
Source Organism
Homo sapiens (Human)
References & Disease Information
Disease
Not specified
PubChem CID
Not available
URL
Not available
PMID
Patent
Not available